ArtNr |
ABC-AO2115a |
Hersteller |
Abcepta
|
Menge |
100 ul |
Kategorie |
|
Typ |
Antibody Primary |
Applikationen |
WB, FC, ELISA |
Clon |
5D10E10 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
PPARA, NR1C1, PPAR, Peroxisome proliferator-activated receptor alpha, Nuclear receptor subfamily 1 group C member 1, PPAR-alpha |
Lieferbar |
|
Primary Accession |
Q07869 |
Application |
WB, FC, E |
Bio References |
1.Blood. 2013 Aug 8; 122(6):969-80.2.Leukemia. 2013 Apr; 27(5):1090-9. |
Clonality |
Monoclonal |
Gene ID |
5465 |
Gene Name |
PPARA |
Subtitle |
Purified Mouse Monoclonal Antibody |
Reactivity |
H |
Legend image 1 |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); |
Type image 1 |
E |
Dilution image 1 |
1/10000 |
Legend image 2 |
Figure 2:Western blot analysis using PPARA mAb against human PPARA (AA: 1-120) recombinant protein. (Expected MW is 38.4 kDa) |
Type image 2 |
WB |
Dilution image 2 |
1/500 - 1/2000 |
Legend image 3 |
Figure 3:Western blot analysis using PPARA mAb against HEK293 (1) and PPARA (AA: 1-120)-hIgGFc transfected HEK293 (2) cell lysate. |
Type image 3 |
WB |
Dilution image 3 |
1/500 - 1/2000 |
Legend image 4 |
Figure 4:Flow cytometric analysis of Jurkat cells using PPARA mouse mAb (green) and negative control (red). |
Type image 4 |
FC |
Dilution image 4 |
1/200 - 1/400 |
Isotype |
IgG1 |
Calculated MW |
52225 |
Formulation |
Purified antibody in PBS with 0.05% sodium azide |
Description |
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. |
|
Clone: 5D10E10 |
Immunogen |
Purified recombinant fragment of human PPARA (AA: 1-120) expressed in E. Coli. |
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