SLC27A2 Antibody

O14975

WB, IHC, E

1. PLoS One. 2011; 6(10):e25865. 2. Eur J Cancer. 2011 Feb; 47(3):420-7.

11001

Purified Mouse Monoclonal Antibody

Black line: Control Antigen (100 ng);
Purple line: Antigen(10ng);
Blue line: Antigen (50 ng);
Red line: Antigen (100 ng);

1/10000

WB

Figure 2: Western blot analysis using SLC27A2 mAb against HEK293 (1) and SLC27A2 (AA: 346-405)-hIgGFc transfected HEK293 (2) cell lysate.

1/500 - 1/2000

IHC

Figure 4: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using SLC27A2 mouse mAb with DAB staining.

1/200 - 1/1000

70312

The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purified recombinant fragment of human SLC27A2 (AA: 346-405) expressed in E. Coli.