ArtNr |
ABC-AO1828a |
Hersteller |
Abcepta
|
Menge |
100 ul |
Kategorie |
|
Typ |
Antibody Primary |
Applikationen |
WB, IHC, ELISA |
Clon |
6B3A9 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
SLC27A2, ACSVL1, FACVL1, FATP2, VLACS, VLCS, Fatty acid transport protein 2, Solute carrier family 27 member 2, Fatty-acid-coenzyme A ligase, Very long-chain acyl-CoA synthetase, FATP-2, very long-chain 1, Long-chain-fatty-acid--CoA ligase, THCA-CoA ligase, Very long-chain-fatty-acid-CoA ligase, 6.2.1.3, 6.2.1.- |
Lieferbar |
|
Primary Accession |
O14975 |
Antigen Type |
Recombinant Protein |
Application |
WB, IHC, E |
Bio Background |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. ; ; |
Bio References |
1. PLoS One. 2011; 6(10):e25865. 2. Eur J Cancer. 2011 Feb; 47(3):420-7. |
Clonality |
Monoclonal |
Gene ID |
11001 |
Gene Name |
SLC27A2 |
Subtitle |
Purified Mouse Monoclonal Antibody |
Reactivity |
H |
Legend image 1 |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); |
Type image 1 |
E |
Dilution image 1 |
1/10000 |
Legend image 2 |
Figure 1: Western blot analysis using SLC27A2 mAb against human SLC27A2 recombinant protein. (Expected MW is 32.4 kDa) |
Type image 2 |
WB |
Dilution image 2 |
1/500 - 1/2000 |
Legend image 3 |
Figure 2: Western blot analysis using SLC27A2 mAb against HEK293 (1) and SLC27A2 (AA: 346-405)-hIgGFc transfected HEK293 (2) cell lysate. |
Type image 3 |
WB |
Dilution image 3 |
1/500 - 1/2000 |
Legend image 4 |
Figure 3: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using SLC27A2 mouse mAb with DAB staining. |
Type image 4 |
IHC |
Dilution image 4 |
1/200 - 1/1000 |
Legend image 5 |
Figure 4: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using SLC27A2 mouse mAb with DAB staining. |
Type image 5 |
IHC |
Dilution image 5 |
1/200 - 1/1000 |
Isotype |
IgG1 |
Calculated MW |
70312 |
Formulation |
Purified antibody in PBS with 0.05% sodium azide |
Description |
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
|
Clone: 6B3A9 |
Immunogen |
Purified recombinant fragment of human SLC27A2 (AA: 346-405) expressed in E. Coli. |
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