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AURKA Antibody

AURKA Antibody

ArtNr	ABC-AO1512a
Hersteller	Abcepta
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, FC, ICC, ELISA
Clon	1F8
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	AURKA, Aurora kinase A, Aurora 2, Aurora/IPL1-related kinase 1, Serine/threonine-protein kinase 6, Breast tumor-amplified kinase, Serine/threonine-protein kinase 15, 2.7.11.1, ARK-1, hARK1, Aurora-related kinase 1, Serine/threonine-protein kinase aurora-A
Lieferbar
Primary Accession	O14965
Antigen Type	Recombinant Protein
Application	WB, FC, ICC, E
Bio References	1. Cell Cycle. 2008 Nov 15; 7(22):3525-33. 2. Oncogene. 2008 Nov 20; 27(51):6539-49.
Clonality	Monoclonal
Gene ID	6790
Gene Name	AURKA
Subtitle	Purified Mouse Monoclonal Antibody
Reactivity	H, Rat, Pr
Legend image 1	Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);
Type image 1	E
Dilution image 1	1/10000
Legend image 2	Figure 1: Western blot analysis using AURKA mouse mAb against HEK293 (1), Sw620 (2), MCF-7 (3), Jurkat (4), Hela (5), HepG2 (6), Cos7 (7) and PC-12 (8) cell lysate.
Type image 2	WB
Dilution image 2	1/500 - 1/2000
Legend image 3	Figure 2: Immunofluorescence analysis of Hela cells using AURKA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
Type image 3	IF
Dilution image 3	1/200 - 1/1000
Legend image 4	Figure 3: Flow cytometric analysis of K562 cells using AURKA mouse mAb (green) and negative control (purple).
Type image 4	FC
Dilution image 4	1/200 - 1/400
Isotype	IgG1
Calculated MW	45809
Formulation	Ascitic fluid containing 0.03% sodium azide.
Description	Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
	Clone: 1F8
Immunogen	Purified recombinant fragment of human AURKA expressed in E. Coli.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AO1512a-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 08.11.2024

Express-Lieferung: 31 Tage sparen

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