ArtNr |
ABC-AO1512a |
Hersteller |
Abcepta
|
Menge |
100 ul |
Kategorie |
|
Typ |
Antibody Primary |
Applikationen |
WB, FC, ICC, ELISA |
Clon |
1F8 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
AURKA, Aurora kinase A, Aurora 2, Aurora/IPL1-related kinase 1, Serine/threonine-protein kinase 6, Breast tumor-amplified kinase, Serine/threonine-protein kinase 15, 2.7.11.1, ARK-1, hARK1, Aurora-related kinase 1, Serine/threonine-protein kinase aurora-A |
Lieferbar |
|
Primary Accession |
O14965 |
Antigen Type |
Recombinant Protein |
Application |
WB, FC, ICC, E |
Bio References |
1. Cell Cycle. 2008 Nov 15; 7(22):3525-33. 2. Oncogene. 2008 Nov 20; 27(51):6539-49. |
Clonality |
Monoclonal |
Gene ID |
6790 |
Gene Name |
AURKA |
Subtitle |
Purified Mouse Monoclonal Antibody |
Reactivity |
H, Rat, Pr |
Legend image 1 |
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng); |
Type image 1 |
E |
Dilution image 1 |
1/10000 |
Legend image 2 |
Figure 1: Western blot analysis using AURKA mouse mAb against HEK293 (1), Sw620 (2), MCF-7 (3), Jurkat (4), Hela (5), HepG2 (6), Cos7 (7) and PC-12 (8) cell lysate. |
Type image 2 |
WB |
Dilution image 2 |
1/500 - 1/2000 |
Legend image 3 |
Figure 2: Immunofluorescence analysis of Hela cells using AURKA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. |
Type image 3 |
IF |
Dilution image 3 |
1/200 - 1/1000 |
Legend image 4 |
Figure 3: Flow cytometric analysis of K562 cells using AURKA mouse mAb (green) and negative control (purple). |
Type image 4 |
FC |
Dilution image 4 |
1/200 - 1/400 |
Isotype |
IgG1 |
Calculated MW |
45809 |
Formulation |
Ascitic fluid containing 0.03% sodium azide. |
Description |
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. |
|
Clone: 1F8 |
Immunogen |
Purified recombinant fragment of human AURKA expressed in E. Coli. |
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