Vergleich

BLK Antibody

ArtNr ABC-AO1487a
Hersteller Abcepta
Menge 100 ul
Kategorie
Typ Antibody Primary
Applikationen WB, FC, ICC, ELISA
Clon 1E6
Specific against other
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products BLK, Tyrosine-protein kinase Blk, B lymphocyte kinase, p55-Blk, 2.7.10.2
Lieferbar
Primary Accession
P51451
Antigen Type
Recombinant Protein
Application
WB, FC, ICC, E
Bio References
1. N Engl J Med. 2008 Feb 28; 358(9):900-9. 2. Genes Immun. 2009 Apr; 10(3):219-26. 3. Proc Natl Acad Sci U S A. 2009 Aug 25; 106(34):14460-5.
Clonality
Monoclonal
Gene ID
640
Gene Name
BLK
Subtitle
Purified Mouse Monoclonal Antibody
Reactivity
H
Legend image 1
Figure 1: Western blot analysis using BLK mAb against HEK293 (1) and BLK(AA: 2-200)-hIgGFc transfected HEK293 (2) cell lysate.
Type image 1
WB
Dilution image 1
1/500 - 1/2000
Legend image 2
Figure 2: Immunofluorescence analysis of Hela cells using BLK mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Type image 2
IF
Dilution image 2
1/200 - 1/1000
Legend image 3
Figure 3: Flow cytometric analysis of HL-60 cells using BLK mouse mAb (green) and negative control (purple).
Type image 3
FC
Dilution image 3
1/200 - 1/400
Isotype
IgG1
Calculated MW
57706
Formulation
Ascitic fluid containing 0.03% sodium azide.
Description
Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development . Activation of B cells by various ligands is accompanied by activation of Blk . It has been suggested that Blk is involved in the control of B cell differentiation and proliferation . Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis . Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response .
Clone: 1E6
Immunogen
Purified recombinant fragment of human BLK expressed in E. Coli.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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