MPS1 Antibody

Recombinant Protein

1. Biochem Cell Biol. 1995 Nov-Dec; 73(11-12):933-47.

2. Mol Biol Cell. 2003 Apr; 14(4):1638-51.

3. Cell. 2008 Jan 25; 132(2):233-46.

6232

Mouse Monoclonal Antibody to MPS1

Figure 1: Confocal immunofluorescence analysis of Hela cells (A), BCBL-1 cells (B) and L1210 cells (C) using MPS1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

1:200~~1000

IF

Mouse IgG1

MPS1, also known as RPS27. It is a ribosomal protein. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. MPS1 is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Purified recombinant fragment of MPS1 expressed in E. Coli.