PPARG Antibody

Recombinant Protein

1. Sarcoidosis Vasc Diffuse Lung Dis. 2006 Jun; 23(2):93-100 2. Hum Biol. 2007 Feb; 79(1):111-9. 3. Hum Genet. 2008 Feb; 123(1):35-40. Epub 2007 Nov 13.

5468

Purified Mouse Monoclonal Antibody

Figure 1: Western blot analysis using PPARG mouse mAb against truncated PPARG-His recombinant protein (1) and full-length PPARG(aa1-477) transfected CHO-K1 cell lysate (2).

1/500 - 1/2000

57620

PPARG: peroxisome proliferator-activated receptor gamma. This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Purified recombinant fragment of PPARG (aa170-270) expressed in E. Coli.