ArtNr |
ABC-AO1113a |
Hersteller |
Abcepta
|
Menge |
100 ul |
Kategorie |
|
Typ |
Antibody Primary |
Applikationen |
WB, IHC, ICC, ELISA |
Clon |
8C4C4 |
Specific against |
other |
Host |
Mouse |
ECLASS 5.1 |
32160702 |
ECLASS 6.1 |
32160702 |
ECLASS 8.0 |
32160702 |
ECLASS 9.0 |
32160702 |
ECLASS 10.0.1 |
32160702 |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
KAT8, MYST1, MOZ, MOZ, YBF2/SAS3, MOF, hMOF, SAS2 and TIP60 protein 1, Histone acetyltransferase KAT8, Lysine acetyltransferase 8, MYST-1, 2.3.1.48 |
Lieferbar |
|
Primary Accession |
Q9H7Z6 |
Antigen Type |
Recombinant Protein |
Application |
WB, IHC, ICC, E |
Bio References |
1. Sterner, D.E., et al. Microbiol. Mol. Biol 2000 Rev. 64: 435-459. 2. Neal, K.C., et al. Biochim. Biophys. 2000 Acta 1490: 170-174. 3. Akhtar, A., et al. EMBO 2001 Rep. 2: 113-118. |
Clonality |
Monoclonal |
Gene ID |
84148 |
Gene Name |
KAT8 |
Subtitle |
Purified Mouse Monoclonal Antibody |
Reactivity |
H |
Legend image 1 |
Figure 1: Western blot analysis using MYST1 mouse mAb against Hela (1), HepG2 (2) and SMMC-7721 (3) cell lysate. |
Type image 1 |
WB |
Dilution image 1 |
1/500 - 1/2000 |
Legend image 2 |
Figure 2: Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), normal esophagus epithelium (B), rectum adenocarcinoma (C), lung squamous cell carcinoma (D), breast infiltrating carcinoma (E), and breast infiltrating carcinoma (F) tissues, showing nuclear localization using MOF/MYST1 mouse mAb with DAB staining. |
Type image 2 |
IHC |
Dilution image 2 |
1/200 - 1/1000 |
Legend image 3 |
Figure 3: Confocal immunofluorescence analysis of Eca 109 cells using MOF/MYST1 mouse mAb (green), showing nuclear localization. |
Type image 3 |
IF |
Dilution image 3 |
1/200 - 1/1000 |
Isotype |
IgG2b |
Calculated MW |
52403 |
Formulation |
Ascitic fluid containing 0.03% sodium azide. |
Description |
MYST1 (MYST histone acetyltransferase 1, MOF) belongs to the MYST family of histone acetyltransferases, which are employed in the cell to bring about transcriptional regulation. The MYST family includes MYST1, is named for the founding members MOZ, yeast YBF2 and SAS2, and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein- protein interactions and targeting transcriptional regulators to chromatin. Although MOF is expressed in both males and females, it associates with the X chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone |
|
Clone: 8C4C4 |
Immunogen |
Purified recombinant fragment of human MYST1 expressed in E. Coli. |
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