FOXP2 Antibody (Ascites)

Synthetic Peptide

This gene encodes a member of the forkhead/winged-helix
(FOX) family of transcription factors. It is expressed in fetal and
adult brain as well as in several other organs such as the lung and
gut. The protein product contains a FOX DNA-binding domain and a
large polyglutamine tract and is an evolutionarily conserved
transcription factor, which may bind directly to approximately 300
to 400 gene promoters in the human genome to regulate the
expression of a variety of genes. This gene is required for proper
development of speech and language regions of the brain during
embryogenesis, and may be involved in a variety of biological
pathways and cascades that may ultimately influence language
development. Mutations in this gene cause speech-language disorder
1 (SPCH1), also known as autosomal dominant speech and language
disorder with orofacial dyspraxia. Multiple alternative transcripts
encoding different isoforms have been identified in this gene.

Monoclonal

93986

Mouse Monoclonal Antibody (Mab)

FOXP2 Antibody(Ascites)(Cat. #AM2116a) western blot analysis in 293 cell line lysates (35μg/lane).This demonstrates the FOXP2 antibody detected the FOXP2 protein (arrow).

1:100~1600

M, Rat

79919

HUMAN

NP_001166237.1; NP_001166238.1; NP_055306.1; NP_683696.2; NP_683697.2; NP_683698.2