Bio Background |
The protein encoded by this gene is a member of theglucuronyltransferase gene family. These enzymes exhibit strictacceptor specificity, recognizing nonreducing terminal sugars andtheir anomeric linkages. This gene product functions as the keyenzyme in a glucuronyl transfer reaction during the biosynthesis ofthe carbohydrate epitope HNK-1 (human natural killer-1, also knownas CD57 and LEU7). Alternate transcriptional splice variants havebeen characterized. |
Bio References |
Akagi, J., et al. Int. J. Clin. Oncol. 15(2):145-152(2010)Petrovas, C., et al. J. Immunol. 183(2):1120-1132(2009)Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)Chong, L.K., et al. Eur. J. Immunol. 38(4):995-1000(2008)Casado, J.G., et al. Tumour Biol. 29(5):304-310(2008) |