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LIN28A Antibody

LIN28A Antibody

ArtNr	ABC-AM1485a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IF, IHC-P
Specific against	other
Host	Mouse
Isotype	IgG1 kappa
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	LIN28, LIN28A, CSDD1, ZCCHC1, Protein lin-28 homolog A, Zinc finger CCHC domain-containing protein 1, Lin-28A
Lieferbar
Primary Accession	Q9H9Z2
Antigen Type	Recombinant Protein
Application	IF, IHC-P, WB
Bio References	Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer. Peng S, et al. Oncogene, 2010 Apr 8. PMID 20101213. Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells. Qiu C, et al. Nucleic Acids Res, 2010 Mar. PMID 19966271. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Iliopoulos D, et al. Cell, 2009 Nov 13. PMID 19878981. TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Heo I, et al. Cell, 2009 Aug 21. PMID 19703396. A role for Lin28 in primordial germ-cell development and germ-cell malignancy. West JA, et al. Nature, 2009 Aug 13. PMID 19578360.
Clonality	Monoclonal
Clone/Animal Names	55CT58.12.1
Gene ID	79727
Gene Name	LIN28A
Subtitle	Purified Mouse Monoclonal Antibody (Mab)
Reactivity	H
Legend image 1	Immunofluorescence analysis of LIN28A Monoclonal Antibody with paraffin-embedded human testis tissue. 0.025 mg/ml primary antibody was followed by PE-conjugated goat anti-mouse lgG (whole molecule). PE emits orange fluorescence.
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of LIN28 recombinant protein by anti-LIN28A Monoclonal Antibody (Cat.#AM1485a). LIN28 (arrow) was detected using the purified Mab.
Type image 2	WB
Dilution image 2	1:200~2000
Legend image 3	Formalin-fixed and paraffin-embedded human testis tissue reacted with LIN28A Monoclonal Antibody (Cat.#AM1485a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~200
Isotype	IgG1 Kappa
Calculated MW	22743
Antigen Source	HUMAN
Target/Specificity	LIN28A recombinant protein is used to produce this monoclonal antibody.
NCBI Accession	NP_078950.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AM1485a-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 08.11.2024

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