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SUMO3 Antibody

SUMO3 Antibody

ArtNr	ABC-AM1201a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Applikationen	WB
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Small ubiquitin-related modifier 3, SUMO-2, SUMO-3, Ubiquitin-like protein SMT3A, Smt3A, SMT3 homolog 1 {ECO:0000312\|HGNC:HGNC:11124}, SUMO3 (HGNC:11124)
Lieferbar
Primary Accession	P55854
Antigen Type	Recombinant Protein
Application	WB
Bio Background	SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).
Bio References	SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress. Han Y, et al. J Biol Chem, 2010 Apr 23. PMID 20181954. Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome. Couch FJ, et al. Cancer Epidemiol Biomarkers Prev, 2010 Jan. PMID 20056645. The p150 subunit of CAF-1 causes association of SUMO2/3 with the DNA replication foci. Uwada J, et al. Biochem Biophys Res Commun, 2010 Jan 1. PMID 19919826. SUMOylation of nuclear actin. Hofmann WA, et al. J Cell Biol, 2009 Jul 27. PMID 19635839. Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity. Brunet Simioni M, et al. Oncogene, 2009 Sep 17. PMID 19597476.
Clonality	Monoclonal
Clone/Animal Names	76AT630.91.31
Gene ID	6612
Gene Name	SUMO3 (HGNC:11124)
Subtitle	Purified Mouse Monoclonal Antibody (Mab)
Reactivity	H
Legend image 1	All lanes : Anti-SUMO3 Antibody at 1:2000 dilution Lane 1: HL-60 whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: 293T/17 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 12 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:2000
Isotype	Mouse IgG1
Calculated MW	11637
Antigen Source	HUMAN
Target/Specificity	Purified recombinant GST-SUMO3 fusion protein was used as immunogen.
NCBI Accession	NP_008867.2

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Menge: 80 ul

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