ArtNr |
ABC-ALS17187 |
Hersteller |
Abcepta
|
Menge |
200 ug |
Kategorie |
|
Typ |
Antibody Primary |
Applikationen |
WB, IF, IHC-P |
Specific against |
other |
Host |
Goat |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
Calnexin, CANX, CNX, IP90, p90 |
Lieferbar |
|
Primary Accession |
P27824 |
Antigen Type |
Recombinant protein |
Application |
WB, IHC-P, IF |
Bio Background |
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse. |
Bio References |
David V., et al.J. Biol. Chem. 268:9585-9592(1993).Tjoelker L.W., et al.Biochemistry 33:3229-3236(1994).Honore B., et al.Electrophoresis 15:482-490(1994).Hansen J.J., et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.Ota T., et al.Nat. Genet. 36:40-45(2004). |
Clonality |
Polyclonal |
Gene ID |
821 |
Gene Name |
CANX |
Subtitle |
Goat Polyclonal Antibody |
Reactivity |
H, M, Rat, Pr, Dog |
Legend image 1 |
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) |
Type image 1 |
IHC-P |
Legend image 2 |
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) |
Type image 2 |
IHC-P |
Legend image 3 |
Immunofluorescence - anti-CANX antibody in Hepa1-6 cells at 1:100 dilution. |
Type image 3 |
IF |
Legend image 4 |
Western blot. |
Type image 4 |
WB |
Isotype |
IgG |
Calculated MW |
67568 |
Target/Specificity |
Detects a band of 90 kDa by Western blot in the following human (293A, primary fibroblasts, HaCat, HeLa, HMEC-1, Jurkat, MNT1, U-118), rat (TR-iBRB), mouse (3T3, AtT-20, Hepa, Raw264.7), monkey (COS-7) and canine (D17) whole cell lysates. |
Purification |
Immunoaffinity purified |
Concentration (mg/ml) |
2 mg/ml |
Reconstitution & Storage |
PBS, 20% glycerol, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Dilution |
IF (1:50 - 1:500), IHC-P (5 µg/ml), WB (1:500 - 1:2000), |
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