Vergleich

CANX / Calnexin Antibody (C-Terminus)

ArtNr ABC-ALS17187
Hersteller Abcepta
Menge 200 ug
Kategorie
Typ Antibody Primary
Applikationen WB, IF, IHC-P
Specific against other
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products Calnexin, CANX, CNX, IP90, p90
Lieferbar
Primary Accession
P27824
Antigen Type
Recombinant protein
Application
WB, IHC-P, IF
Bio Background
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse.
Bio References
David V., et al.J. Biol. Chem. 268:9585-9592(1993).
Tjoelker L.W., et al.Biochemistry 33:3229-3236(1994).
Honore B., et al.Electrophoresis 15:482-490(1994).
Hansen J.J., et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Ota T., et al.Nat. Genet. 36:40-45(2004).
Clonality
Polyclonal
Gene ID
821
Gene Name
CANX
Subtitle
Goat Polyclonal Antibody
Reactivity
H, M, Rat, Pr, Dog
Legend image 1
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Type image 1
IHC-P
Legend image 2
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Type image 2
IHC-P
Legend image 3
Immunofluorescence - anti-CANX antibody in Hepa1-6 cells at 1:100 dilution.
Type image 3
IF
Legend image 4
Western blot.
Type image 4
WB
Isotype
IgG
Calculated MW
67568
Target/Specificity
Detects a band of 90 kDa by Western blot in the following human (293A, primary fibroblasts, HaCat, HeLa, HMEC-1, Jurkat, MNT1, U-118), rat (TR-iBRB), mouse (3T3, AtT-20, Hepa, Raw264.7), monkey (COS-7) and canine (D17) whole cell lysates.
Purification
Immunoaffinity purified
Concentration (mg/ml)
2 mg/ml
Reconstitution & Storage
PBS, 20% glycerol, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Dilution
IF (1:50 - 1:500), IHC-P (5 µg/ml), WB (1:500 - 1:2000),

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ug
Lieferbar: In stock
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