ArtNr |
ABC-ALS14143 |
Hersteller |
Abcepta
|
Menge |
50 ug |
Kategorie |
|
Typ |
Antibody Primary |
Applikationen |
WB, IP, ELISA, IHC-P |
Clon |
1D1-C12 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
SAP-1, PSAP, Protein C, SAP1, Protein A, GLBA, Prosaposin, A1 activator, Cerebroside sulfate activator, Co-beta-glucosidase, Component C, CSAct, Dispersin, Glucosylceramidase activator, Proactivator polypeptide, SAP-2, Saposin-D, Sphingolipid activator protein 1, Sphingolipid activator protein 2, Saposin-B-Val, Sulfatide/GM1 activator, Saposin-A, Saposin-B, Saposin-C |
Lieferbar |
|
Primary Accession |
P07602 |
Application |
WB, IHC-P, E, IP |
Bio Background |
Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12). Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases. |
Bio References |
Rorman E.G., et al.Genomics 5:486-492(1989).Nakano T., et al.J. Biochem. 105:152-154(1989).Kalnine N., et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.Ebert L., et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.Deloukas P., et al.Nature 429:375-381(2004). |
Clonality |
Monoclonal |
Gene ID |
5660 |
Gene Name |
PSAP |
Subtitle |
Mouse Monoclonal Antibody |
Reactivity |
H |
Legend image 1 |
Western blot of PSAP expression in transfected 293T cell line by PSAP monoclonal antibody clone... |
Type image 1 |
WB |
Legend image 2 |
Anti-PSAP antibody IHC of human adrenal. |
Type image 2 |
IHC |
Calculated MW |
58113 |
Target/Specificity |
Human PSAP |
|
Clone: 1D1-C12 |
Purification |
Protein A purified |
Concentration (mg/ml) |
0.43 mg/ml |
Reconstitution & Storage |
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Dilution |
IHC-P (5 µg/ml) |
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