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CHRNA9 antibody - N-terminal region

CHRNA9 antibody - N-terminal region

ArtNr	ABC-AI16203
Hersteller	Abcepta
Menge	50 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CHRNA9, NACHRA9, Neuronal acetylcholine receptor subunit alpha-9, Nicotinic acetylcholine receptor subunit alpha-9, NACHR alpha-9
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Primary Accession	Q9UGM1
Application	WB
Bio Background	Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane (PubMed:11752216, PubMed:25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane (PubMed:11752216, PubMed:25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion (PubMed:11021840).
Bio References	Sgard F., et al.Mol. Pharmacol. 61:150-159(2002). Lustig L.R., et al.Cytogenet. Genome Res. 98:154-159(2002). Hillier L.W., et al.Nature 434:724-731(2005). Nguyen V.T., et al.Am. J. Pathol. 157:1377-1391(2000). Peng H., et al.Life Sci. 76:263-280(2004).
Clonality	Polyclonal
Gene ID	55584
Gene Name	CHRNA9
Subtitle	Rabbit Polyclonal Antibody
Reactivity	M, Rb, Hs, B, Gp, Dog
Legend image 1	WB Suggested Anti-CHRNA9 Antibody Titration: 0.0625?g/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysate
Type image 1	WB
Other Accession	NM_017581; NP_060051
Predicted	M, Rb, Hs, B, Gp, Dog
Calculated MW	54807
Immunogen	The immunogen for anti-CHRNA9 antibody: synthetic peptide directed towards the N terminal of human CHRNA9
Purification	Affinity Purified
Protein Size	479
Partner Proteins	CHRNA4, CHRNA2, CHRNA4, CRELD2
Nucleotide Accession Num	NM_017581
Protein Accession Num	NP_060051
Alias Symbol	NACHRA9, HSA243342
Reconstitution & Storage	Add 50 ul of distilled water. Final anti-CHRNA9 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.

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ABC-AI16203-datasheet.pdf

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Menge: 50 ug

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