Vergleich

Phospho-Cofilin-S3 Antibody

ArtNr ABC-AE1009b
Hersteller Abcepta
Menge 0.1 mg
Kategorie
Typ Antibody Primary
Format affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.
Applikationen WB, IF, IHC
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products CFL1, p18, Cofilin, CFL, Cofilin-1, 18 kDa phosphoprotein, non-muscle isoform
Lieferbar
Primary Accession
P23528
Application
WB, IHC, IF
Bio Background
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Bio References
Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture. Garg P, et al. J Biol Chem, 2010 Jul 16. PMID 20472933. Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 May 14. PMID 20471030. Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 Apr 8. PMID 20381070. HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1. Quintela-Fandino M, et al. Proc Natl Acad Sci U S A, 2010 Feb 9. PMID 20133759. Tyrosine phosphorylation of cofilin at Y68 by v-Src leads to its degradation through ubiquitin-proteasome pathway. Yoo Y, et al. Oncogene, 2010 Jan 14. PMID 19802004.
Clonality
Polyclonal
Gene ID
1072
Gene Name
CFL1
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M, Rat
Legend image 1
Western blot analysis of extracts from COLO205 cells using Cofilin Phospho-Cofilin-S3 Antibody (Cat#AE1009b)(Lane 2)and the same antibody preincubated with blocking peptide(Lane 1).
Type image 1
WB
Dilution image 1
1:500~1:1000
Legend image 2
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Phospho-Cofilin-S3 Antibody (Cat#AE1009b).
Type image 2
IHC
Dilution image 2
1:50~1:100
Legend image 3
Immunofluorescence staining of methanol-fixed HeLa cells using Phospho-Cofilin-S3 Antibody
Type image 3
IF
Dilution image 3
1:100~200
Isotype
Rabbit IgG
Target/Specificity
The antibody was affinity-purified from rabbit antiserum using epitope-specific phosphopeptide column, and the antibody against non-phosphopeptide was removed using non-phosphopeptide column corresponding to the phosphorylation site.
NCBI Accession
NP_005498.1
Concentration (mg/ml)
1mg/ml
Sequence
Peptide sequence around phosphorylation site of serine 3 (M-A-S(p)-G-V), according to the protein. NP_005498.1

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen