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Anti-PSD95 Antibody

Anti-PSD95 Antibody

ArtNr	ABC-ABO11603
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Lyophilized
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PSD-95, PSD95, DLG4, Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, SAP-90, SAP90
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Primary Accession	P78352
Application	WB, IHC-P
Clonality	Polyclonal
Gene ID	1742
Reactivity	H, M, Rat
Legend image 1	Anti-PSD95 antibody, ABO11603, IHC(P)IHC(P): Human Intestinal Cancer Tissue
Type image 1	IHC
Dilution image 1	0.5-1 µg/ml
Legend image 2	Anti-PSD95 antibody, ABO11603, IHC(P)IHC(P): Human Mammary Cancer Tissue
Type image 2	IHC
Dilution image 2	0.5-1 µg/ml
Legend image 3	Anti-PSD95 antibody, ABO11603, IHC(P)IHC(P): Human Placenta Tissue
Type image 3	IHC
Legend image 4	Anti-PSD95 antibody, ABO11603, All Western blottingAll lanes: Anti-DLG4 (ABO11603) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 80KDObserved bind size: 100KD
Type image 4	WB
Calculated MW	80495
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description	Rabbit IgG polyclonal antibody for Disks large homolog 4(DLG4) detection. Tested with WB, IHC-P in Human; Mouse; Rat.
Protein Function	Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity). .
Subcellular Localization	Cell membrane ; Peripheral membrane protein . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Cell projection, axon . Cell junction, synapse . High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells.
Tissue Specificity	Brain.
Protein Name	Disks large homolog 4
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human PSD95(492-507aa RRVERREWSRLKAKDW), identical to the related rat and mouse sequences.
Purification	Immunogen affinity purified.
Cross Reactivity	No cross reactivity with other proteins
Storage	At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Sequence Similarities	Belongs to the MAGUK family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-ABO11603-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 04.10.2024

Express-Lieferung: 14 Tage sparen

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