ArtNr |
ABC-ABO10817 |
Hersteller |
Abcepta
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Lyophilized |
Applikationen |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
IGFBP3, IGF-binding protein 3, IGFBP-3, IBP3, Insulin-like growth factor-binding protein 3, IBP-3 |
Lieferbar |
|
Primary Accession |
P17936 |
Application |
WB, IHC-P |
Clonality |
Polyclonal |
Gene ID |
3486 |
Reactivity |
H |
Legend image 1 |
Anti-IGFBP-3 antibody, ABO10817, Western blottingAll lanes: Anti IGFBP-3 (ABO10817) at 0.5ug/mlLane 1: 293T Whole Cell Lysate at 40ugLane 2: MCF- 7 Whole Cell Lysate at 40ugLane 3: A549 Whole Cell Lysate at 40ugLane 4: SW620 Whole Cell Lysate at 40ugPredicted bind size: 32KDObserved bind size: 40KD |
Type image 1 |
WB |
Dilution image 1 |
0.1-0.5 µg/ml |
Legend image 2 |
Anti-IGFBP-3 antibody, ABO10817, IHC(P)IHC(P): Human Mammary Cancer Tissue |
Type image 2 |
IHC |
Dilution image 2 |
0.5-1 µg/ml |
Calculated MW |
31674 |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Description |
Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 3(IGFBP3) detection. Tested with WB, IHC-P in Human. |
Protein Function |
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. . |
Subcellular Localization |
Secreted . |
Tissue Specificity |
Expressed by most tissues. Present in plasma. |
Protein Name |
Insulin-like growth factor-binding protein 3(IBP-3/IGF-binding protein 3/IGFBP-3) |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Immunogen |
A synthetic peptide corresponding to a sequence in the middle region of human IGFBP-3(182-198aa IKKGHAKDSQRYKVDYE). |
Purification |
Immunogen affinity purified. |
Cross Reactivity |
No cross reactivity with other proteins |
Storage |
At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing. |
Concentration (mg/ml) |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Sequence Similarities |
Contains 1 IGFBP N-terminal domain. |
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