Vergleich

Anti-IGFBP-3 Antibody

ArtNr ABC-ABO10817
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Format Lyophilized
Applikationen WB, IHC-P
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products IGFBP3, IGF-binding protein 3, IGFBP-3, IBP3, Insulin-like growth factor-binding protein 3, IBP-3
Lieferbar
Primary Accession
P17936
Application
WB, IHC-P
Clonality
Polyclonal
Gene ID
3486
Reactivity
H
Legend image 1
Anti-IGFBP-3 antibody, ABO10817, Western blottingAll lanes: Anti IGFBP-3 (ABO10817) at 0.5ug/mlLane 1: 293T Whole Cell Lysate at 40ugLane 2: MCF- 7 Whole Cell Lysate at 40ugLane 3: A549 Whole Cell Lysate at 40ugLane 4: SW620 Whole Cell Lysate at 40ugPredicted bind size: 32KDObserved bind size: 40KD
Type image 1
WB
Dilution image 1
0.1-0.5 µg/ml
Legend image 2
Anti-IGFBP-3 antibody, ABO10817, IHC(P)IHC(P): Human Mammary Cancer Tissue
Type image 2
IHC
Dilution image 2
0.5-1 µg/ml
Calculated MW
31674
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description
Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 3(IGFBP3) detection. Tested with WB, IHC-P in Human.
Protein Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. .
Subcellular Localization
Secreted .
Tissue Specificity
Expressed by most tissues. Present in plasma.
Protein Name
Insulin-like growth factor-binding protein 3(IBP-3/IGF-binding protein 3/IGFBP-3)
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human IGFBP-3(182-198aa IKKGHAKDSQRYKVDYE).
Purification
Immunogen affinity purified.
Cross Reactivity
No cross reactivity with other proteins
Storage
At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Sequence Similarities
Contains 1 IGFBP N-terminal domain.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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