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Anti-CCR5 Antibody

Anti-CCR5 Antibody

ArtNr	ABC-ABO10512
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Lyophilized
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CCR-5, CCR5, CMKBR5, C-C chemokine receptor type 5, CHEMR13, HIV-1 fusion coreceptor, C-C CKR-5, CC-CKR-5, CD195
Lieferbar
Primary Accession	P51681
Application	WB
Clonality	Polyclonal
Gene ID	1234
Reactivity	H
Legend image 1	Anti-CCR5 antibody, ABO10512, Western blottingLane 1: COLO320 Cell LysateLane 2: MCF-7 Cell LysateLane 3: SMMC Cell LysateLane 4: JURKAT Cell Lysate
Type image 1	WB
Dilution image 1	0.1-0.5 µg/ml
Calculated MW	40524
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description	Rabbit IgG polyclonal antibody for C-C chemokine receptor type 5(CCR5) detection. Tested with WB in Human.
Protein Function	Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. .
Subcellular Localization	Cell membrane ; Multi-pass membrane protein .
Tissue Specificity	Highly expressed in spleen, thymus, in the myeloid cell line THP-1, in the promyeloblastic cell line KG-1a and on CD4+ and CD8+ T-cells. Medium levels in peripheral blood leukocytes and in small intestine. Low levels in ovary and lung. .
Protein Name	C-C chemokine receptor type 5
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen	A synthetic peptide corresponding to a sequence in the middle region of human CCR5(179-197aa SSHFPYSQYQFWKNFQTLK).
Purification	Immunogen affinity purified.
Cross Reactivity	No cross reactivity with other proteins
Storage	At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Sequence Similarities	Belongs to the G-protein coupled receptor 1 family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-ABO10512-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 08.11.2024

Express-Lieferung: 29 Tage sparen

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