ArtNr |
ABC-ABO10448 |
Hersteller |
Abcepta
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Lyophilized |
Applikationen |
WB, ICC, IHC-P, IHC-F |
Clon |
F4 |
Specific against |
other |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
Multidrug resistance protein 3, P-glycoprotein 3, Mdr3, Pgy3, Abcb4, Mdr1a, Pgy-3, Multidrug resistance protein 1A, ATP-binding cassette sub-family B member 1A, Abcb1a, 3.6.3.44, MDR1A |
Lieferbar |
|
Primary Accession |
P21447 |
Application |
WB, IHC-P, IHC-F, ICC |
Clonality |
Monoclonal |
Gene ID |
18671 |
Reactivity |
H |
Isotype |
Mouse IgG1 |
Calculated MW |
140647 |
Reconstitution |
Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
Description |
Mouse IgG monoclonal antibody for P-Glycoprotein (MDR), ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1 ) detection. Tested with WB, IHC-P, IHC-F, ICC in Human. No cross reactivity with other proteins. |
Protein Function |
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. . |
Subcellular Localization |
Cell membrane; Multi-pass membrane protein. |
Tissue Specificity |
ABCB1: Expressed in liver, kidney, small intestineand brain. |
Protein Name |
Multidrug resistance protein 1 |
Contents |
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. |
|
Clone: F4 |
Immunogen |
Mixture of human and hamster drug-resistant whole cells and crude plasma membranes. |
Purification |
Ascites |
Cross Reactivity |
No cross reactivity with other proteins |
Storage |
At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing. |
Concentration (mg/ml) |
Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
Sequence Similarities |
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. |
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