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Semaphorin-4D/CD100 Rabbit mAb Europäischer Partner

ArtNr A24404-200uL
Hersteller Abclonal
Menge 200 uL
Quantity options 100 uL 200 uL 20 uL 50 uL
Kategorie
Typ Antibody Monoclonal
Applikationen FC, IF, ICC, ELISA
Specific against Human (Homo sapiens)
Isotype IgG
Purity Affinity purification
Sequence MAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYNFLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLK
NCBI SEMA4D
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias SEMA4D, C9orf164, CD100, M-sema-G, SEMAJ, coll-4, semaphorin-4D, Semaphorin-4D/CD100
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Monoclonal Antibodies
Shipping Temperature
ice pack
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Background
Plexin-B1 is related to axon guidance in the central nervous system. The Sema4D function is also widely detected in the immune system and was found to be the first semaphorin expressed on the surface of many types of immune cells. In the immune system, CD72 is a low-affinity receptor for Sema4D, and studies have shown that Sema4D can not only regulate T cell activation, but also participate in the regulation of B cell survival and differentiation. In the immune system, soluble fragments containing extracellular domains produced by proteolytic cleavage can regulate many physiological functions of Sema4D. Sema4D is also associated with tumorigenesis because studies have confirmed that it is overexpressed in various types of solid tumor cells. To some extent, the role of Sema4D in tumorigenesis is related to its ability to cause tumor angiogenesis, cell invasion, and immunosuppression by enhancing bone marrow-derived suppressor cell function.
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-734 of human Semaphorin-4D/CD100(NP_006369.3).
Recommended Dilution
FC, 1:50 - 1:200
Protein Size
82kDa/96kDa
Route
Recombinant protein
Manufacturer - Research Area
Cell Biology & Developmental Biology, Apoptosis, Immunology & Inflammation, CD markers, Neuroscience, Cell Type Marker,

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 uL
Lieferbar: In stock
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