Transforming Growth Factor-Beta 1 Human Recombinant, CHO

Product Name: Transforming Growth Factor-Beta 1 Human Recombinant, CHO
Synonyms: Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB, TGF-b 1, LAP, TGFB1.
Description: TGFB1 Human Recombinant produced in CHO cells is a homodimeric polypeptide chain containing 2 x 112 amino acids and having a total molecular mass of 25kDa. 
Uniprot Accesion Number: P01137
Amino Acid Sequence:ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS
Source: Chinese Hamster Ovary cells.
Physical Appearance and Stability: Store at 4C if entire vial will be used within 2-4 weeks.  Store, frozen at -20C for longer periods of time.  For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Formulation and Purity: The TGF b 1 Human 0.22 um filtered solution (0.24mg/ml) contains 20mM TRIS HCl buffer pH 7.2. Greater than 95% as determined by SDS-PAGE.
Application:
Solubility:
Biological Activity: The ED50 for this effect is typically 20-60ng/ml before activation and 0.1-1ng/ml after activation as measured by TGF-b1¿s ability to inhibit the mouse IL-4-dependent proliferation of HT-2 cells.Activation: Activated in vitro at pH below 3.5 and over 12.5.
Shipping Format and Condition: Lyophilized powder at room temperature.
Usage Statement: Our products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.