Mouse Monoclonal Antibody to CD122

Catalog Number: sAP-1723
Product Name: Mouse Monoclonal Antibody to CD122
Target Molecle: CD122
Aliases: IL2RB; IL15RB; P70-75
Species: Human;
MW: 61kDa
Enterez GeneID: 3560
General Information: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression.
Immunogen: Purified recombinant fragment of human CD122 (AA: extra 27-240) expressed in E. Coli.
Clone: MM1G11C6
Isotype: Mouse IgG2b
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstitued with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; ICC: N to A; FCM: 1 to 200 - 1 to 400; IHC: N to A
References: 1.Curr Opin Hematol. 2015 Jan; 22(1):53-9. 2.BMC Cancer. 2013 May 28; 13:261.