Mouse Monoclonal Antibody to CD207

Catalog Number: sAP-1668
Product Name: Mouse Monoclonal Antibody to CD207
Target Molecle: CD207
Aliases: CLEC4K
Species: Human;
MW: 36.7kDa
Enterez GeneID: 50489
General Information: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Immunogen: Purified recombinant fragment of human CD207 (AA: extra 155-328) expressed in E. Coli.
Clone: MM1C5A1
Isotype: Mouse IgG2b
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstitued with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; ICC: N to A; FCM: 1 to 200 - 1 to 400; IHC: N to A
References: 1.Cancer Med. 2014 Feb; 3(1):14-24.2.Eur J Obstet Gynecol Reprod Biol. 2012 Oct; 164(2):180-4.