Mouse Monoclonal Antibody to GAD2

Catalog Number: sAP-1180
Product Name: Mouse Monoclonal Antibody to GAD2
Target Molecle: GAD2
Aliases: GAD65
Species: Human;
MW: 65.4kDa
Enterez GeneID: 2572
General Information: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.;
Immunogen: Purified recombinant fragment of human GAD2 (AA: 1-100) expressed in E. Coli.
Clone: MM5D9G12;
Isotype: Mouse IgG1
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstitued with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: ; ICC: ; FCM: 1 to 200 - 1 to 400
References: 1.Histopathology. 2013 Sep; 63(3):334-42. ; 2.Biol Psychiatry. 2012 Nov 1; 72(9):734-43.;