Mouse Monoclonal Antibody to NEFH

Mouse IgG1

MW: 112.4kDa
Enterez GeneID: 4744
General Information: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. ; ;
Immunogen: Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: Propose dilution 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: 1 to 200 - 1 to 1000
References: 1.Int J Exp Pathol. 2011 Oct; 92(5):326-32. 2.Stem Cell Res. 2009 May; 2(3):211-8.