Goat anti-KCNQ5 Antibody

Goat anti-KCNQ5 Antibody
Principle Name: KCNQ5
Official Symbol: KCNQ5
All Name and Symbols: KCNQ5; potassium voltage-gated channel, KQT-like subfamily, member 5; Kv7.5; OTTHUMP00000016729; OTTHUMP00000064152; OTTHUMP00000064153; potassium channel protein
Accession Number(s): NP_062816.2; NP_001153602.1; NP_001153604.1; NP_1153605.1; NP_001153606.1
Peptide Sequence: ESTDALSLPHVKLK, is from C Terminus
Human Gene ID(s): 56479
Non-Human GeneID(s): 226922 (mouse); 259273 (rat);
Important Comments: This antibody is expected to cross-react with isoform 1, 2, 3, 4 and 5 (NP_062816.2; NP_001153602.1; NP_001153604.1; NP_1153605.1; NP_001153606.1).
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA
Peptide ELISA: antibody detection limit dilution 1 to 64000.
Western Blot: Preliminary experiments gave an approx. 22kDa band in Human Brain (Hippocampus and Cerebral Cortex) and Human Skeletal Muscle lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literat
Reference(s): Schuetz F, Kumar S, Poronnik P, Adams DJ. Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1. Am J Physiol Cell Physiol. 2008 Jul; 295(1):C73-80.PMID: 18463232