ArtNr |
ARP-28-10104-5 |
Hersteller |
American Research Products
|
Menge |
5 ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Lieferbar |
|
Description |
Chemerin is a secreted chemoattractant protein that can signal through the chemokine like receptor-1 (CMKLR1). It is expressed in various tissues, including white adipose tissue, and circulates in blood as an inactive 143 amino acid precursor protein. Biologically active Chemerin is generated by proteolytic removal of C-terminal residues by several circulating proteases. Chemerin acts as a chemoattractant for cells expressing the CMKLR1 receptor, which includes certain dendritic cells, macrophages, and adipocytes. Recombinant human Chemerin is a 15.6 kDa protein consisting of 135 amino acid residues. |
Storage |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Synonyms |
Tazarotene-induced gene 2 (TIG2), RARRES2 |
Purity |
0, 98 |
Source |
E. Coli |
Interest Fields |
Chemotaxis, Diabetes / Weight Regulation, Immune System , Lipid Metabolism |
Amino Acid Sequence |
ELTEAQRRGL QVALEEFHKH PPVQWAFQET SVESAVDTPF PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA CIKLGSEDKV LGRLVHCPIE TQVLREAEEH QETQCLRVQR AGEDPHSFYF PGQFA |
Endotoxin Level |
Endotoxin level is <, 0.1 ng/ug of protein (<, 1EU/ug). |
Biological Activity |
Determined by its ability to chemoattract human immature dendritic cells using a concentration range of 1.0-100.0 ng/ml. |
Protein Content |
Verified by UV Spectroscopy and/or SDS-PAGE gel. |
Authenticity |
Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.