Hersteller |
American Research Products
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Menge |
100 ug |
ArtNr |
ARP-11-IL-2MHT-100 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Description |
Interleukin-2 (IL-2), also known as T cell growth factor (TCGF), is an immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant mouse IL-2 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
Form |
Liquid. In Phosphate Buffered Saline (pH7.4) containing 20% glycerol, 0.1M NaCl |
Storage |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Synonyms |
IL-2, T-cell growth factor, TCGF, Il-2, Interleukin-2, il2, interleukin 2, il 2 |
Concentration |
0.5 mg/ml (determined by Bradford assay) |
NCBI |
NP_032392 |
References |
- Morgan DA., et al. (1976). Science. 193, 1007-8.
- Watson J., et al. (1980). Immunol Rev. 51, 257-78.
- Taniguchi T., et al. (1983). Nature. 302, 305-10.
|
Antigen Recognized in Species |
Mouse |
Purity |
>, 90% by SDS - PAGE |
Molecular Weight |
19.5 kDa (170 aa), confirmed by MALDI-TOF. |
Amino Acid Sequence |
MGSSHHHHHH SSGLVPRGSH MAPTSSSTSS STAEAQQQQQ QQQQQQQHLE QLLMDLQELL SRMENYRNLK LPRMLTFKFY LPKQATELKD LQCLEDELGP LRHVLDLTQS KSFQLEDAEN FISNIRVTVV KLKGSDNTFE CQFDDESATV VDFLRRWIAF CQSVISTSPQ |
Gene Category |
Hormones &, Cytokines |
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