ArtNr |
ARP-01-P2617-100 |
Hersteller |
American Research Products
|
Menge |
100 ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Lieferbar |
|
Description |
IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism Recombinant human IRF5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Form |
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT |
Storage |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Synonyms |
interferon regulatory factor 5 isoform b, SLEB10 |
Concentration |
0.25 mg/ml (determined by Bradford assay) |
NCBI |
NP_116032.1 |
References |
- Barnes B.J., et al (2001). J. Biol. Chem. 276:23382-23390
- Schoenemeyer A., et al (2005). J. Biol. Chem. 280:17005-17012
|
Antigen Recognized in Species |
Human |
Purity |
>, 85 % by SDS - PAGE |
Molecular Weight |
10.7 kDa (101aa) confirmed by MALDI-TOF |
Amino Acid Sequence |
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSPPTL QPPTLQPPVV LGPPAPDPSP LAPPPGNPAG FRELLSEVLE PGPLPASLPP AGEQLLPDLL I |
Gene Category |
Epigenomics (Transcription &, Translation) |
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