ArtNr |
ARP-01-P1384-0.5 |
Hersteller |
American Research Products
|
Menge |
0.5 mg |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Lieferbar |
|
Description |
LRPAP1, also known as alpha-2-macroglobulin receptor-associated protein, belongs to the alpha-2-MRAP family. This protein interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330. It is present on the cell surface forming a complex with the alpha 2 macroglobulin receptor heavy and light chains In complex with the alpha 2 MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis Recombinant human LRPAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
Form |
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT |
Storage |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Synonyms |
alpha-2-macroglobulin receptor-associated protein, A2MRAP, A2RAP, HBP44, MGC138272, MRAP, RAP |
Concentration |
1.0 mg/ml (determined by Bradford assay) |
NCBI |
NP_002328 |
References |
- Vash B. et al. (1998) Blood 92: 3277-3285.
- Trommsdorff M. et al. (1999) Cell 97: 689-701.
|
Antigen Recognized in Species |
Human |
Purity |
>, 90% by SDS - PAGE |
Molecular Weight |
40.4 kDa(348aa) confirmed by MALDI-TOF |
Amino Acid Sequence |
MGSSHHHHHH SSGLVPRGSH MGSHMYSREK NQPKPSPKRE SGEEFRMEKL NQLWEKAQRL HLPPVRLAEL HADLKIQERD ELAWKKLKLD GLDEDGEKEA RLIRNLNVIL AKYGLDGKKD ARQVTSNSLS GTQEDGLDDP RLEKLWHKAK TSGKFSGEEL DKLWREFLHH KEKVHEYNVL LETLSRTEEI HENVISPSDL SDIKGSVLHS RHTELKEKLR SINQGLDRLR RVSHQGYSTE AEFEEPRVID LWDLAQSANL TDKELEAFRE ELKHFEAKIE KHNHYQKQLE IAHEKLRHAE SVGDGERVSR SREKHALLEG RTKELGYTVK KHLQDLSGRI SRARHNEL |
Gene Category |
Metabolism |
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