Description |
FABP-6 is a cytosolic protein that binds bile acids with a high affinity. In the small intestine, its expression is restricted to the ileum where it is involved in the enterohepatic circulation of bile acids. Alternate transcription promoters generate two transcript variants, encoding a 128 aa and a 177 aa residue protein. Human FABP6 isoform 2 contains 128 amino acid residues and is believed to be acetylated on Ala2. It binds both fatty acids and bile acids and has roles in fatty acid transport and metabolism. Recombinant human FABP-6 was expressed in E.coli and purified by using conventional chromatography techniques. |
Synonyms |
I-BABP, I-15P, ILLBP, ILBP, ILBP3, I-BAP, I-BALB, Fatty acid binding protein 6, Gastrotropin, FABP6, Fatty acid binding protein 6 Fatty acid binding protein 6, ileal (gastrotropin), GT, I 15P, I BABP, I BALB, I BAP, I15P, IBABP, IBALB, IBAP, ILBP, Ileal lipid binding protein, Intestinal 15 kDa protein, Intestinal bile acid binding protein. |