ArtNr |
ARP-01-2076-20 |
Hersteller |
American Research Products
|
Menge |
20 ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Lieferbar |
|
Description |
Pentraxin 3(PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins and containing a unique N-terminal domain. Pentraxin 3 is produced and released at inflammatory sites by diverse cell types including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. It plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. Recombinant human Pentraxin 3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
Form |
Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT 10% glycerol. |
Storage |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Synonyms |
TNFAIP5, TSG-14, Pentraxin 3, AI607804, Pentaxin 3, Pentaxin-related protein PTX3, Pentraxin-related gene, rapidly induced by IL-1 beta, Pentraxin-related gene, PTX3, TSG14, Tumor necrosis factor-inducible gene 14 protein, Tumor necrosis factor-inducible protein TSG-14 |
Concentration |
1 mg/ml (determined by Bradford assay) |
NCBI |
NP_002843 |
References |
- Imamura M., et al. (2007). Cell Immunol. 248(2):86-94.
- Allens VV., et al. (1994). Blood. 84(10):3483-93.
|
Antigen Recognized in Species |
Human |
Purity |
>, 90% by SDS - PAGE |
Molecular Weight |
44.4 kDa (401aa), confirmed by MALDI-TOF. |
Amino Acid Sequence |
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMENS DDYDLMYVNL DNEIDNGLHP TEDPTPCDCG QEHSEWDKLF IMLENSQMRE RMLLQATDDV LRGELQRLRE ELGRLAESLA RPCAPGAPAE ARLTSALDEL LQATRDAGRR LARMEGAEAQ RPEEAGRALA AVLEELRQTR ADLHAVQGWA ARSWLPAGCE TAILFPMRSK KIFGSVHPVR PMRLESFSAC IWVKATDVLN KTILFSYGTK RNPYEIQLYL SYQSIVFVVG GEENKLVAEA MVSLGRWTHL CGTWNSEEGL TSLWVNGELA ATTVEMATGH IVPEGGILQI GQEKNGCCVG GGFDETLAFS GRLTGFNIWD SVLSNEEIRE TGGAESCHIR GNIVGWGVTE IQPHGGAQYV S |
Gene Category |
Immunology |
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