Description |
CERT is a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Recombinant human CERT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Synonyms |
COL4A3BP, CERTL, GPBP, STARD11, Collagen, type IV, alpha 3 binding protein Alpha 3 type IV collagen binding protein, Ceramide transporter, CERT, Cert protein, Collagen type IV alpha 3 (Goodpasture antigen) binding protein, Collagen type IV alpha 3 binding protein, FLJ20597, Goodpasture antigen binding protein, Lipid transfer protein CERTL, Procollagen type IV alpha 3 (Goodpasture antigen) binding protein, StAR related lipid transfer protein 11, StARD 11, START domain containing 11, START domain containing protein 11, |