Anti-NUCB2

Nucelobindin-2 (Nesfatin-1) was first isolated in adipocytes, but is also expressed by gastric mucosa and pancreatic beta-cells. This pattern of nucelobindin-2 expression, as well as the presence of nucelobindin-2 within the plasma of rodents and humans, strongly suggests that this compound may act as a circulating regulatory factor. Nucelobindin-2 is reported to reduce food intake after administration. It is responsible for regulating appetite and production of body fat. Excess nucelobindin-2 in the brain leads to a loss of appetite, lack of nesfatin-1 in the brain leads to an increase of appetite.

Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

Optimal conditions must be determined individually for each application.

DNA-binding Protein NEFA, Nucleobindin-2, Nesfatin