ArtNr |
ARP-10-P1385 |
Hersteller |
American Research Products
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
other |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Lieferbar |
|
Description |
Rabbit IgG polyclonal antibody for Metalloproteinase inhibitor 1 ( TIMP1) detection. Tested with WB, IHC-P in Human. |
Background |
TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. TIMP was found to be located about 22 cM proximal to OTC (300461). |
Immunogen |
A synthetic peptide corresponding to a sequence at the C-terminal of human TIMP1. |
Form |
Lyophilized |
Specificity |
Human. No cross reactivity with other proteins. |
Storage |
2-8C. For long term -20C after reconstitution. |
Synonyms |
Erythroid-potentiating activity |
References |
1. TIMP1 TIMP metallopeptidase inhibitor 1 |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Purification |
Immunogen affinity purified. |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
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