ArtNr |
ARP-10-M1018 |
Hersteller |
American Research Products
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Monoclonal |
Specific against |
other |
Host |
Mouse |
Isotype |
IgG1 |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Lieferbar |
|
Background |
Cell division sycle(CDC25) gene product is a protein-tyrosine phosphatase, activates a partially purified p34(cdc2)/cyclin B complex. The cdc25 protein also shares homology with a protein phosphatase with activity against both tyrosine and serine (and thus probably threonine) phosphate residues. CDC25C is expressed predominantly in G2 phase in healer cells. The human gene encodes a protein with a predicted molecular mass of 53, 000 daltons whose C-terminal domain shares about 37% sequence identity with the fission yeast cdc25 mitotic inducer. CDC25C gene is mapped to 5q31. |
Immunogen |
Recombinant human Cdc25c. |
Form |
Lyophilized |
Specificity |
Human. No cross reactivity with other proteins. |
Storage |
2-8C. For long term -20C after reconstitution. |
Synonyms |
CDC25, PPP1R60, MITOSIS INDUCER CDC25, cell division cycle 25C, protein phosphatase 1, regulatory subunit 60, Dual specificity phosphatase Cdc25C |
References |
- 1. Sartor, H., Ehlert, F., Grzeschik, K.-H., Muller, R., Adolph, S. : Assignment of two human cell cycle genes, CDC25C and CCNB1, to 5q31 and 5q12, respectively. Genomics 13: 911-912, 1992.
- 2. Taviaux, S. A., Demaille, J. G. : Localization of human cell cycle regulatory genes CDC25C to 5q31 and WEE1 to 11p15.3-11p.15.1 by fluorescence in situ hybridization. Genomics 15: 194-196, 1993.
|
Reconstitution |
1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
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