Vergleich

MIN-6 cells

ArtNr C0018008
Hersteller Addexbio
Menge One Frozen vial
Kategorie
Typ Tumour Cells
Specific against Mouse (Murine, Mus musculus)
Dry ice Yes
Citations 1.Ishihara, H., Asano, T., Tsukuda, K. et al. (1993). Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets. Diabetologia 36(11), 1139-1145.
2. Bao L, Fu X, Si M, Wang Y, Ma R, Ren X, Lv H. MicroRNA-185 Targets SOCS3 to Inhibit Beta-Cell Dysfunction in Diabetes. PLoS One. 2015 Feb 6;10(2):e0116067. PMID: 25658748
3.Mayer C, Bergholdt R, Cucak H, Rolin BC, Sams A, Rosendahl A.Neutralizing Anti-IL20 Antibody Treatment Significantly Modulates Low Grade Inflammation without AffectingHbA1c in Type 2 Diabetic db/db Mice. PLoS One. 2015 Jul 10;10(7):e0131306. PMID: 26162095
4. Fortin JS, Benoit-Biancamano MO, C-Gaudreault R. Discovery of ethyl urea derivatives as inhibitors of islet amyloid polypeptide fibrillization and cytotoxicity. Can J Physiol Pharmacol. 2016 Mar;94(3):341-346. PMID: 26679837
5. Chang TJ, Tseng HC, Liu MW, Chang YC, Hsieh ML, Chuang LM. Glucose-like peptide-1 prevents methylglyoxal-induced apoptosis of beta cells through improvingmitochondrial function and suppressing prolonged AMPK activation.Sci Rep. 2016 Mar 21;6:23403. doi: 10.1038/srep23403. PMID: 26997114
6. Huang LP, Kirschke CP. Down-regulation of zinc transport 8 (SLC30A8) in pancreatic beta-cells promotes cell survival. Austin Journal of Endocrinology and Diabetes. 2016;3(1):1037.
7. Silvander JSG, Kvarnström SM, Kumari-Ilieva A, Shrestha A, Alam CM, Toivola DM. Keratins regulate beta-cell mitochondrial morphology, motility, and homeostasis. FASEB J. 2017 Oct;31(10):4578-4587. PMID: 28666985
8. Elliott AD, Bedard N, Ustione A, Baird MA, Davidson MW, Tkaczyk T, Piston DW. Hyperspectral imaging for simultaneous measurements of two FRET biosensors in pancreatic beta-cells. PLoS One. 2017 Dec 6;12(12):e0188789. doi: 10.1371/journal.pone.0188789. PMID: 29211763
9. Velasquez C, Vasquez JS, Balcazar N. In Vitro Effect of Fatty Acids Identified in the Plasma of Obese Adolescents on the Function of Pancreatic beta-Cells. Diabetes Metab J. 2017 Aug;41(4):303-315. doi: 10.4093/dmj.2017.41.4.303. PMID: 28868828
ECLASS 10.1 32160890
ECLASS 11.0 32160890
UNSPSC 41106509
Lieferbar
Description

Disease:

Insulinoma (SV40 T-antigen induced cell immortalization)

Origin:

Pancreatic Islets

Species:

Mus musculus

Tissue:

Pancreas

Morphology:

beta cells

Properties:

Adherent

Medium:

AddexBio-Advanced Medium (C0003-04) + other components critical to the cell growth listed on the datasheet.

Subculture:

1:2 to 1:3 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37C

Freezing Medium:

Culture medium supplemented with 20% (v/v) FBS and 7.5% (v/v) DMSO

Biosafety Level:

II

Sterility:

Bacteria: Negative

Yeast: Negative

Mycoplasma: Negative

Pathogens:

HIV: Negative

Hepatitis B: Negative

Hepatitis C: Negative

Insulin Responsiveness:

Express glucokinase and Glut2.

Related cells by Organ:

AR-42J cells

BxPc-3 cells

Capan-1 cells

MIA PaCa-2 cells

E3LZ10.7 cells

A10.7 cells

INS-1 cells

MIN-6 cells

Storage condition
LN2
Manufacturers Category
Cell Lines

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: One Frozen vial
Lieferbar: In stock
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