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SH-Sy5y cells

SH-Sy5y cells

ArtNr	C0005004
Hersteller	Addexbio
Menge	One Frozen vial
Kategorie	Oncology Cell Lines & Cell Culture Cell Lines By Organ Lung Cancer Bladder Cancer Bone Cancer
Typ	Tumour Cells
Specific against	Human (Homo sapiens)
Dry ice	Yes
Citations	1.Harris, B., Pereira, I., and Parkin, E. Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein. Brain Res, 1296: 203-215, 2009. 2.Hettiarachchi, N. T., Parker, A., Dallas, M. L., Pennington, K., Hung, C. C., Pearson, H. A., Boyle, J. P., Robinson, P., and Peers, C. alpha-Synuclein modulation of Ca2+ signaling in human neuroblastoma (SH-SY5Y) cells. J Neurochem, 111: 1192-1201, 2009. 3.Kim, I. S., Koppula, S., Park, P. J., Kim, E. H., Kim, C. G., Choi, W. S., Lee, K. H., and Choi, D. K. Chrysanthemum morifolium Ramat (CM) extract protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity. J Ethnopharmacol, 126: 447-454, 2009. 4.Myers, T. A., Kaushal, D., and Philipp, M. T. Microglia are mediators of Borrelia burgdorferi-induced apoptosis in SH-SY5Y neuronal cells. PLoS Pathog, 5: e1000659, 2009. 5.Wu, F., Poon, W. S., Lu, G., Wang, A., Meng, H., Feng, L., Li, Z., and Liu, S. Alpha-synuclein knockdown attenuates MPP+ induced mitochondrial dysfunction of SH-SY5Y cells. Brain Res, 1292: 173-179, 2009. 6.Yang, W., Tiffany-Castiglioni, E., Koh, H. C., and Son, I. H. Paraquat activates the IRE1/ASK1/JNK cascade associated with apoptosis in human neuroblastoma SH-SY5Y cells. Toxicol Lett, 191: 203-210, 2009. 7. McDonald RL, Vanghan PF, Peers C. Muscarinic (M1) receptor-mediated inhibition of K(+)-evoked [3H]-noradrenaline release from human nuuroblastoma (SH-Sy5y) cells via inhibition of L- and N-type Ca2+ channels. Br J Pharmacol 113:459 621-627, 1994.
ECLASS 10.1	32160890
ECLASS 11.0	32160890
UNSPSC	41106509
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Description	Disease: Neuroblastoma Origin: Derived from metastatic bone marrow Species: Homo sapiens Tissue: Brain Morphology: Epithelial Properties: Adherent+suspension Cytogenic data: Patient: Female, 4 yrs of age Medium: Ham's F12:AddexBio-formulated EMEM (C0005-01) (1:1) + 15% FBS Subculture: 1:10 to 1:100 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37C Freezing Medium: Complete culture medium supplemented with 5% (v/v) DMSO Biosafety Level: I Application: SH-Sy5y cell line is a thrice-cloned sub-line of bone marrow biopsy-derived SK-N-SH. SH-Sy5y has a dopamine-beta-hydroxylase activity and can convert glutamate to GABA. Will form tumors in nude mice in approximately 3-4 weeks. Sterility: Bacteria: Negative Yeast: Negative Mycoplasma: Negative Pathogens: HIV: Negative Hepatitis B: Negative Hepatitis C: Negative DNA Profile (STR): Amelogenin: X; CSF1PO: 11; D13S317: 11; D16S539: 8, 13; D5S818: 12; D7S820: 7, 10; THO1: 7, 10; TPOX: 8, 11; vWA: 14, 18 Citation Format: If use of this culture results in a scientific publication, it should be cited in the publication as: SH-Sy5y (AddexBio C0005006) Mutations in SH-Sy5y Cells Related cells by Organ: B103 LN-319 SH-Sy5y cells U87MG cells
Storage condition	LN2
Manufacturers Category	Cell Lines

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Menge: One Frozen vial

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