Vergleich

Rat BMP-2 protein

ArtNr ABK-PRP120126-1mg
Hersteller Abbkine Scientific
Menge 1mg
Kategorie
Typ Proteins
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
Sequence
Amino acid sequence derived from mature form of human BMP2 (NP_001191.1) (Gln283-Arg396) was expressed. The mature form sequences of human, mouse, rat, rhesus and canine BMP2 are identical.
Activity
Measured by its ability to induce alkaline phosphatase production by MC3T3-E1 mouse osteoblastic cells. The ED50 for this effect is typically 0.5-2 ug/ml.
Protein length
The recombinant human BMP2 monomer consists of 115 amino acids and has a predicted molecular mass of 13 kDa.
Preparation method
E. coli
Purity
> 95 % as determined by SDS-PAGE
Formulation
Lyophilized from sterile 30 % CAN, 0.1 % TFA, pH 2.9.
Molecular weight
13 kDa
Usage notes
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Rat BMP-2 protein in sterile ddH2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Storage instructions
Lyophilized Rat BMP-2 protein product should be stored desiccated below -18C. Upon reconstitution, the protein should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Shipping
The product is shipped at ambient temperature.
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Background
BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
Gene ID
650
Alternative
BDA2; BDA2A; BMP-2; BMP2A; Bone morphogenetic protein 2; BMP2
Accession
P12643

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1mg
Lieferbar: In stock
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