ArtNr |
ABK-ABP58418-200ul |
Hersteller |
Abbkine Scientific
|
Menge |
200ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Applikationen |
ELISA, Western Blot |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Lieferbar |
|
Immunogen |
Synthesized peptide derived from part region of human DRA protein at amino acid sequence of 100-180 |
Applications notes |
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000). |
Purification |
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
Formulation |
Liquid solution |
Concentration |
1 mg/ml |
Storage buffer |
PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol. |
Storage instructions |
Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
Shipping |
Gel pack with blue ice. |
Precautions |
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
Background |
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. |
Gene ID |
3122 |
Alternative |
HLA class II histocompatibility antigen; DR alpha chain; MHC class II antigen DRA |
Other info |
The antibody detects endogenous levels of DRA protein |
Accession |
P01903 |
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