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ERa (phospho Ser305) Polyclonal Antibody

ArtNr ABK-ABP54175-200ul
Hersteller Abbkine Scientific
Menge 200ul
Kategorie
Typ Antibody Polyclonal
Applikationen IF, ELISA
Specific against Human
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ESR1, ESR, NR3A1, Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1
Lieferbar
Accession
P03372
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Background
ESR1 encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The estrogen receptor 1 localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
Clonality
Polyclonal
Concentration
1 mg/ml
Description
Rabbit Anti-ERa (phospho Ser305) Polyclonal Antibody
Formulation
Liquid solution
Gene ID
2099
Immunogen
Synthesized peptide derived from human ERa around the phosphorylation site of S305
Others
Phospho-ERa (S305) Polyclonal Antibody detects endogenous levels of ERa protein only when phosphorylated at S305.
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Storage Buffer
PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instructions
Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Tag
Estrogen receptor

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200ul
Lieferbar: In stock
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Lieferung vsl. bis 13.09.2024 

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