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TSC2 (pS939) Antibody

TSC2 (pS939) Antibody

ArtNr	abx031975-400
Hersteller	Abbexa
Menge	400 ul
Quantity options	400 ul 80 ul
Kategorie	Antibodies Immunofluorescence Immunocytochemistry Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	ELISA, DB, IF/ICC
Specific against	Human
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TSC2 (phospho-Ser939)
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Manufacturers Category	Primary Antibodies
Description	Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.
Dry Ice	No
Buffer	PBS containing 0.09% sodium azide.
Clonality	Polyclonal
Molecular Weight	Calculated MW: 201 kDa
Note	This product is for research use only.
Purification	Purified by protein A affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with peptides. The antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Specificity	Predicted to react with Mouse TSC2.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Target Information	TSC2 (pS939)
UniProt Entry Name	TSC2_HUMAN

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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