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Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody Europäischer Partner

ArtNr abx031271-400
Hersteller Abbexa
Menge 400 ul
Quantity options 400 ul 80 ul
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IF, ICC, ELISA
Specific against Human
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products MBD2
Lieferbar
Manufacturers Category
Primary Antibodies
Description
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.
Dry Ice
No
Buffer
PBS containing 0.09% sodium azide.
Clonality
Polyclonal
Gene Symbol
MBD2
Molecular Weight
Calculated MW: 43.3 kDa
Note
This product is for research use only.
Purification
Purified through a protein A column, followed by peptide affinity purification.
Specificity
Predicted to react with Mouse MBD2.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Target Information
Methyl-CpG Binding Domain Protein 2 (MBD2)
UniProt Entry Name
MBD2_HUMAN

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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