Sodium Voltage-Gated Channel Beta Subunit 1 (SCN1B) Antibody

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. SCN1B encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Purified through a protein A column, followed by peptide affinity purification.

Q07699

PBS containing 0.09% sodium azide.

This product is for research use only.