Mineralocorticoid Receptor (NR3C2) Antibody

NR3C2 Antibody is a Rabbit Polyclonal antibody against NR3C2. This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.

PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.

NR3C2

This product is for research use only.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

MCR_HUMAN